Prospects for dengue vaccines for travelers
نویسندگان
چکیده
Travel-acquired dengue cases have been increasing as the overall global dengue burden has expanded. In Korea, imported dengue cases have been reported since 2000 when it first became a notifiable disease. During the first four months of 2016, three times more dengue cases were reported in Korea than during the same period the previous year. A safe and efficacious vaccine for travelers would be beneficial to prevent dengue disease in individual travelers and potentially decrease the risk of virus spread to non-endemic areas. Here, we summarize the characteristics of dengue vaccines for travelers and review dengue vaccines currently licensed or in clinical development.
منابع مشابه
Regional Variation in Travel-related Illness acquired in Africa, March 1997–May 2011
To understand geographic variation in travel-related illness acquired in distinct African regions, we used the GeoSentinel Surveillance Network database to analyze records for 16,893 ill travelers returning from Africa over a 14-year period. Travelers to northern Africa most commonly reported gastrointestinal illnesses and dog bites. Febrile illnesses were more common in travelers returning fro...
متن کاملDengue virus infection among long-term travelers from the Netherlands: A prospective study, 2008-2011
BACKGROUND Dengue is increasing rapidly in endemic regions. Data on incidence among travelers to these areas are limited. Five prospective studies have been performed thus far, mainly among short-term travelers. OBJECTIVE To obtain the attack and incidence rate (AR, IR) of dengue virus (DENV) infection among long-term travelers and identify associated risk factors. METHODS A prospective stu...
متن کاملPhenomenological analysis of going home in Caribbean-American international travelers
BACKGROUND In travel health risk assessments visiting friends and relatives (VFR) travel status is often used as an indicator for high-risk travel behavior. VFR travelers have been associated with increased risk of travel-associated illnesses due to poor adherence to travel guidelines and lack of pre-travel health consultations. For travelers to dengue endemic regions, guidelines include compli...
متن کاملDengue vaccines: Problems & prospects
639 Dengue virus (DV) infect ion is most ly asymptotic or produces a mild self-limiting acute febrile illness, dengue fever (DF), and a lifethreatening severe illness, dengue haemorrhagic fever (DHF) with minor or major bleeding from different sites. DHF has emerged as the most important arbovirus disease in man in the last three decades. It has been estimated that about 50 to 100 million cases...
متن کاملIllness in travelers returned from Brazil: the GeoSentinel experience and implications for the 2014 FIFA World Cup and the 2016 Summer Olympics.
BACKGROUND Brazil will host the 2014 FIFA World Cup and the 2016 Olympic and Paralympic Games, events that are expected to attract hundreds of thousands of international travelers. Travelers to Brazil will encounter locally endemic infections as well as mass event-specific risks. METHODS We describe 1586 ill returned travelers who had visited Brazil and were seen at a GeoSentinel Clinic from ...
متن کامل